An open or closed case for HMGA

An open or closed case for HMGA

An open or closed case for HMGA S enescence turns a chromatin-activating protein towards the dark side. Upon senescence induction, high mobility group A (HMGA) protein helps to make silent heterochromatin, report Masashi Narita, Scott Lowe, and colleagues (Cold Spring Harbor Laboratory, NY). HMGA proteins promote open and active chromatin, are highly expressed in the early embryo, and can promo...

Thinking Animals: A Closed Case or an Open Debate?

Comparative Cognition was born out of a meeting on animal thinking through the Ernst Strüngmann Forum. The Forum’s main objective is for the continual advancement of scientific knowledge facilitated by bringing together leading experts to address high-priority areas of interest from multiple vantage points. Editors Menzel and Fischer proposed a Forum on comparative cognition to address key topi...

Copular Complements: Closed or Open?

In this paper, we present some preliminary observations on the syntactic analysis of copular constructions in LFG. We suggest several conclusions and directions for future research. First, the open analysis is appropriate for some copular constructions but not for others, even within the same language. Second, the same construction can be open in some languages and closed in others. Third, we c...

Electroencephalographic modulations during an open- or closed-eyes motor task

There is fundamental knowledge that during the resting state cerebral activity recorded by electroencephalography (EEG) is strongly modulated by the eyes-closed condition compared to the eyes-open condition, especially in the occipital lobe. However, little research has demonstrated the influence of the eyes-closed condition on the motor cortex, particularly during a self-paced movement. This p...

Intensive Care Units: Open or Closed?